Alanine
What is alanine?
Alanine is a naturally occurring, non-essential amino acid, meaning the body can make it on its own. But, both supplementally, and when used in skincare, it can have many benefits.
Alanine also plays a role in physical performance and muscle health.
Alanine at a glance:
- It occurs naturally in the human body
- Is an amino acid and natural building block of protein
- Supports skin structure and appearance
- Helps skin retain moisture
- Known for its calming feel when applied topically
Alanine for health
Outside of skincare, alanine also supports physical performance, particularly in its beta-alanine form. Beta-alanine is commonly used to help the body cope with high-intensity exercise by supporting muscle endurance and delaying the effects of fatigue (5).
By increasing levels of carnosine in the muscles, beta-alanine helps buffer the outcomes of intense activity, making demanding workouts feel more sustainable over time (6).
Health and performance benefits of Alanine
- Supporting short, high-intensity activities such as sprinting, HIIT and cycling
- Helping delay muscle fatigue during demanding exercise
- Improving overall work capacity and endurance
- Supporting muscle health and function in ageing adults
- It may also boost mental and physical resilience under stress
Key takeaways
Alanine is a versatile amino acid with many benefits. In skincare, it supports hydration, comfort and structure. Meanwhile, in health and performance it plays a role in endurance and muscle support.
Academic References
- Ahsan H. Immunopharmacology and immunopathology of peptides and proteins in personal products. J Immunoassay Immunochem. 2019;40(4):439-447. doi: 10.1080/15321819.2019.1629590. Epub 2019 Jun 17. PMID: 31204576. https://pubmed.ncbi.nlm.nih.gov/31204576/
- Gasmi A, Mujawdiya PK, Lysiuk R, Shanaida M, Peana M, Piscopo S, Beley N, Dzyha S, Smetanina K, Shanaida V, Resimont S, Bjorklund G. The Possible Roles of β-alanine and L-carnosine in Anti-aging. Curr Med Chem. 2025;32(1):6-22. doi: 10.2174/0109298673263561231117054447. PMID: 38243982. https://pubmed.ncbi.nlm.nih.gov/38243982/
- Lee C, Pei L, Park H, Kim H, Huh CS. Skin Protection Effects of Lactobacillus paragasseri HN910 Lysate and the Role of Alanine. Probiotics Antimicrob Proteins. 2025 Apr 17. doi: 10.1007/s12602-025-10533-2. Epub ahead of print. PMID: 40244537. https://pubmed.ncbi.nlm.nih.gov/40244537/
- Pintea A, Manea A, Pintea C, Vlad RA, Bîrsan M, Antonoaea P, Rédai EM, Ciurba A. Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence: A Review. Biomolecules. 2025 Jan 9;15(1):88. doi: 10.3390/biom15010088. PMID: 39858482; PMCID: PMC11762834. https://pmc.ncbi.nlm.nih.gov/articles/PMC11762834/
- Hobson RM, Saunders B, Ball G, Harris RC, Sale C. Effects of β-alanine supplementation on exercise performance: a meta-analysis. Amino Acids. 2012 Jul;43(1):25-37. doi: 10.1007/s00726-011-1200-z. Epub 2012 Jan 24. PMID: 22270875; PMCID: PMC3374095.https://pmc.ncbi.nlm.nih.gov/articles/PMC3374095/
- Culbertson JY, Kreider RB, Greenwood M, Cooke M. Effects of beta-alanine on muscle carnosine and exercise performance: a review of the current literature. Nutrients. 2010 Jan;2(1):75-98. doi: 10.3390/nu2010075. Epub 2010 Jan 25. PMID: 22253993; PMCID: PMC3257613.https://pmc.ncbi.nlm.nih.gov/articles/PMC3257613/