Coenzyme Q10 (CoQ10)

Coenzyme Q10 (CoQ10) is a naturally occurring, vitamin-like compound found in every cell of your body, with the highest concentrations in energy-intensive organs like the heart, liver, and kidneys. It is often described as the body's spark plug because it facilitates the conversion of food into usable energy (1).

CoQ10 is most strongly supported as an adjunct therapy for congestive heart failure. Some studies show it can reduce hospitalisations and risk concerning heart related complications when taken alongside standard treatments. It may also modestly lower systolic blood pressure (2).cognitive function.

Multiple trials suggest that taking CoQ10 daily can reduce the frequency and duration of migraine attacks. It typically takes around three months of consistent use to see these effects (3).

In men, research suggests it may improve sperm motility and concentration. In women, it is often studied for improving egg quality and success rates in assisted reproductive technologies such as IVF (in vitro fertilisation, a medical process that supports conception) (4,5).

Many people take CoQ10 to counter health problems like muscle aches caused by statin medications. It’s worth noting that, while some individual trials show benefit, some researchers claim that scientific evidence remains as yet inconclusive (6,7).

Research has explored CoQ10 and its use in Parkinson’s and Alzheimer’s. This is because it plays an essential role in cellular energy production by supporting ATP (adenosine triphosphate, the molecule cells use as energy). Its antioxidant properties help protect cells from oxidative stress, which is damage caused by unstable molecules known as free radicals (8,9).

CoQ10 is generally considered safe. Research doses typically range from 100 mg to 400 mg daily. Doses over 100 mg are often divided throughout the day to improve absorption and reduce mild stomach upset. Additionally, it may reduce the effectiveness of blood thinners like Warfarin. If you are taking medication, or if you have any concerns, consult a qualified health provider before starting, especially if you have a history of heart or kidney disease (10,11).

In summary, naturopathic practitioners often recommend CoQ10 for mitochondrial support in conditions such as fibromyalgia and chronic fatigue syndrome (12), aiming to restore energy production and reduce oxidative stress. It is also used to support healthy ageing as levels decline with age (13), and in metabolic health for Type 2 diabetes or PCOS to support insulin sensitivity and cholesterol balance (14). It may also be suggested for gum disease to help reduce inflammation and periodontal pocket depth (15).

CoQ10 supports cellular energy and antioxidant protection. The strongest evidence from studies for its use include for heart health and migraine prevention.

Please note, it is best taken with food containing fat for optimal absorption (16).