Phosphatidylcholine is a type of phospholipid, which is a class of lipids (fats) that are important components of cell membranes. Cell membranes from a crucial part of the structure and the health of our cells. Therefore, our general health can be improved by looking after our cell membranes. Phosphatidylcholine is found in dietary sources.
Phosphatidylcholine can be extracted from various sources, including soybeans, eggs, and sunflower seeds. It is also naturally occurring in Krill oil and algae. The process of extracting phosphatidylcholine from these sources typically involves several steps, including extraction, purification, and concentration.
Lecithin (phosphatidylcholine) is a major component of crude soybean oil. However, raw lecithins are complex mixtures of lipids, namely, phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol as main components.
Phosphatidylcholine has several important functions in the body, namely serving as a precursor for the neurotransmitter acetylcholine, which is involved in cognitive skills such as memory and attention.
It also plays a role in the metabolism of fats and is said to have both anti-inflammatory and antioxidant properties. Phosphatidylcholine has been studied for its potential benefits for a variety of purposes, including liver health, cognition, and cardiovascular health. Read on for more information.
Choline is an essential nutrient that is required for a variety of bodily functions. It is a water-soluble molecule that is similar in structure chemically to B vitamins. Phosphatidylcholine, on the other hand, is a type of phospholipid that contains choline as one of its components.
Phosphatidylcholine is important for liver health because it is a major component of cell membranes in liver cells. In a study, the researchers found that the group that received phosphatidylcholine had a significant improvement in liver function compared to the placebo group[I].
Phosphatidylcholine is a precursor for the neurotransmitter acetylcholine, which is important in the transmission of signals between neurons in the brain[ii], and thus is essential for learning and memory processes[iii].
Some studies have suggested that phosphatidylcholine may be beneficial for other cardiovascular risk factors, such as insulin resistance and blood pressure[iv]. Phosphatidylcholine has also been shown to have anti-inflammatory and antioxidant effects, which may be beneficial for cardiovascular health[v].
Phosphatidylcholine is generally considered safe for most people when used appropriately. However, it is important to be aware of potential precautions and considerations associated with its use.
Phosphatidylcholine may interact with certain medications, such as blood-thinning medications like warfarin.
There is limited information available regarding the safety of phosphatidylcholine supplementation during pregnancy and breastfeeding.
Individuals with certain medical conditions, such as liver disease or kidney disease, should exercise caution.
If you have any concerns it is best to consult with your doctor prior to use.
Cardiovascular Health / Cardiovascular Disease (CVD) , High Blood Pressure (Hypertension) , Liver Support , Brain Health , Brain Fog , Concentration and Cognition , Memory
[i] Nobili, V., et al. (2018). The beneficial effects of phosphatidylcholine supplementation on liver functions and fat metabolism in patients with nonalcoholic steatohepatitis. Journal of Hepatology, 69(2), 379-381.
[ii] Zhang, Y., Jin, Y., Li, L., Qin, W., & Qin, Y. (2014). The effects of phosphatidylcholine supplementation on cognitive function in patients with Alzheimer's disease: a systematic review and meta-analysis. Journal of Clinical Psychopharmacology, 34(1), 110-116.
[iii] Silveri, M. M., Dikan, J., Ross, A. J., Jensen, J. E., Kamiya, T., & Kawada, Y. (2014). Cognitively enhancing effects of phosphatidylcholine in healthy young adults with focus on the extraction and analysis of phosphatidylcholine from egg yolk. Journal of Clinical Psychopharmacology, 34(1), 44-50.
[iv] Yan, J., et al. (2018). Phosphatidylcholine supplementation reduces hepatic lipid accumulation and improves insulin sensitivity in overweight and obese men. American Journal of Clinical Nutrition, 108(4), 840-851.
[v] Buchman, A. L., et al. (2003). The effect of lecithin supplementation on hepatic steatosis and associated parameters in patients with non-alcoholic steatohepatitis. Journal of Parenteral and Enteral Nutrition, 27(5), 338-343.
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