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Pernicious anemia

Nutritional Information about B12 Deficiency, which is also known as Pernicious Anemia. Recommended supplements below ...

Pernicious Anaemia: Causes, Symptoms & Best Ways to Support B12 Levels

Pernicious anaemia is a type of B12 deficiency caused by poor absorption, leading to fatigue, memory issues, and enlarged red blood cells. Learn about symptoms, causes, and the best dietary and supplement solutions.

How does B12 deficiency or insufficiency lead to Pernicious Anaemia?

B12 absorption requires hydrochloric acid in the stomach and intrinsic factor, a compound produced by parietal cells that binds with B12 to facilitate absorption in the small intestine.

What is megaloblastic anaemia?

As a subgroup of megaloblastic anaemia, pernicious anaemia leads to enlarged red blood cells.

Symptoms often include extreme fatigue, poor concentration, and memory issues. Despite being a water-soluble vitamin, B12 can be stored in the body for some time[i], meaning symptoms may take a while to develop.

Vegan diets are typically low in vitamin B12, so incorporating algaes or supplementation may help prevent deficiency.

Nutritional support for pernicious anaemia

If a B12 deficiency is diagnosed, dietary changes and supplementation may be necessary.

Best Food Sources of Vitamin B12

Vitamin B12 found in sea vegetables is not efficiently utilised by the body and should not be relied upon for supplementation.

B12 Supplementation & Medical Support

For more on related deficiencies, see Therapedia’s article on Anemia for Iron Deficiency.

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Please note that the information contained within this website does not and should not replace medical advice, and is not intended to treat or diagnose. We always recommend you consult with your doctor. Our Nutritional Therapy team is highly trained and we offer one to one Nutritional Therapy Consultations, which are designed to be complementary to any medical treatment from a functional medicine approach, as well as offering a preventative & optimal health focus.